Inclusion criteria | Exclusion criteria |
---|---|
a) Apparently healthy individuals with normal body weight for age | a) Haemoglobin < 10 gm/dl or Haematocrit < 30% |
b) W. bancrofti microfilaraemia (in one millilitre of venous blood collected between 8.30 and 9.30 p.m.) | b) Symptoms/signs of any chronic illness |
c) Normal electro-cardiogram (ECG) | c) Patients with a history of any drug intolerance, reaction or allergy |
d) Normal chest X-ray | d) Presence of cysts or ova of intestinal helminths by routine stool examination |
e) Results within normal limits in routine stool and urine examination | e) Patients giving history of consuming either albendazole or DEC in the preceding year |
f) Results within normal limits for haemoglobin concentration, total white blood cell count, differential count, absolute eosinophil count, erythrocyte sedimentation rate, packed cell volume | f) Declared unfit by physician for any other reason. |
g) Results within normal limits for blood urea, glucose, bilirubin, creatinine, cholesterol; serum sodium, potassium, chloride, protein, albumin, globulin, serum glutamic pyruvic transaminase, alkaline phosphatase |