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Table 2 Comparison of the day specific mean oedema volume between patients treated with Daflon (500 mg) + DEC (25 mg) and patients treated with DEC (25 mg), twice daily for 90 days.

From: Some observations on the effect of Daflon (micronized purified flavonoid fraction of Rutaceae aurantiae) in bancroftian filarial lymphoedema

Days of comparison

Daflon 500 mg + DEC

DEC

 

t – value

P value

t – value

P value

day 0 vs. day 75

0.316

0.758

-0.140

0.891

day 0 vs. day 90

2.928

0.013

0.001

0.999

day 0 vs. day 180

4.149

0.002

0.521

0.612

day 0 vs. day 270

4.989

< 0.001

0.156

0.879

day 0 vs. day 360

6.959

< 0.001

0.428

0.676

day 75 vs. day 90

2.574

0.026

0.433

0.673

day 75 vs. day 180

3.309

0.007

1.291

0.221

day 180 vs. day 270

0.621

0.547

-1.003

0.336

day 270 vs. day 360

0.325

0.751

-0.006

0.996

  1. Day 0: pre-treatment Day 1 – day 90: period of treatment Day 91 – day 360: period of follow-up