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a) Patients with unilateral lower limb lymphoedema (of either grade I/II minimum for six months†) from area highly endemic for bancroftian filariasis.
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a) Haemoglobin less than 10 gm/dl or haematocrit < 30%.
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b) Patients looking apparently healthy except as (a) above and with normal body weight as per age.
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b) Clinical exclusion of patients with lymphoedema due to any other known aetiology other than filariasis (such as venous insufficiency, varicose ulcers).
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c) Patients with normal electro-cardiogram (ECG).
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d) Patients with normal chest X-ray.
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c) Patients presenting with acute adenolymphangitis at the time of recruitment.
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e) Results within normal limits in routine stool and urine examination.
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d) Patients with a history of taking Daflon or DEC in the past 3 months.
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f) Results within normal limits for haemoglobin concentration, total white blood cell count, differential count, absolute eosinophil count, erythrocyte sedimentation rate, packed cell volume.
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e) Symptoms / signs of any other chronic illness
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g) Results within normal limits for blood urea, sugar, bilirubin, creatinine, cholesterol, serum sodium, potassium, chloride, protein, albumin, globulin, pyruvic transaminase, alkaline phosphatase.
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f) Patients with a history of any drug intolerance, reaction or allergy.
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