Skip to main content

Advertisement

Table 1 Comparison among IgG4 reactivities of BmR1, Ov-BmR1 and Ll-BmR1 using a panel of serum samples from patients with various parasitic infections and healthy controls (endemic and non-endemic normals). BmR1 is the antigen expressed by Bm17DIII DNA sequence; while Ov-BmR1 and Ll-BmR1 are the antigens expressed by the homologs of Bm17DIII DNA sequence in O. volvulus and L. loa respectively.

From: Homologs of the Brugia malayi diagnostic antigen BmR1 are present in other filarial parasites but induce different humoral immune responses

Serum type No Positive by BmR1 (%) Positive by Ov-BmR1 and Ll-BmR1 (%)
O. volvulus, mf positive 70 1 (1.43) 1 (1.43)
L. loa, mf positive 14 6 (42.86) 6 (42.86)
W. bancrofti, mf positive 33 8 (24.24) 8 (24.24)
B. malayi, mf positive 28 28 (100) 28 (100)
Trichuris trichiura 8 0 0
Ascaris lumbricoides 8 0 0
Mixed infection with T. trichuris, A. lumbricoides and hookworm 8 0 0
Entamoeba histolytica (invasive) 11 0 0
Toxocara 14 0 0
Gnathostoma spinigerum 1 0 0
Strongyloides stercoralis 6 0 0
Endemic normals (healthy controls) 29 0 0
Non-endemic normals (healthy controls) 32 0 0
TOTAL 262