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Table 2 Results of ELISAs to detect IgG1, IgG2 and IgG3 anti-filarial antibodies in serum samples from patients with various helminthiasis and healthy controls (non-endemic normals) using BmR1, Ov-BmR1 and Ll-BmR1. All antigens (tested separately) demonstrated identical results with all serum samples.

From: Homologs of the Brugia malayi diagnostic antigen BmR1 are present in other filarial parasites but induce different humoral immune responses

Type of serum sample

Number of positive results out of number of samples tested

 

IgG1-ELISA

IgG2-ELISA

IgG3-ELISA

O. volvulus mf+

47/47

0/21

0/21

L. loa mf+

14/14

0/14

0/14

W. bancrofti mf+

6/6

0/6

0/6

W. bancrofti chronic

6/6

0/6

0/6

B. malayi mf+

10/10

0/10

0/10

B. malayi chronic

14/14

0/14

0/14

Soil-transmitted helminth infections

10/10

0/10

0/10

Non-endemic normals (healthy controls)

10/10

0/10

0/10