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Table 1 Sensitivity and Specificity of Antibody Assays1

From: Recombinant antigen-based antibody assays for the diagnosis and surveillance of lymphatic filariasis – a multicenter trial

Infection Bm14 ELISA Positive/Tested (%) SXP Cassette Positive/Tested (%) BmR1 ELISA Positive/Tested (%) BmR1 Dipstick Positive/Tested (%)
W. bancrofti (n = 35)2 32/35 (91%) 30/33 (2 NC) (91%) 14/31 (4 NC) (45%) 17/30 (5NC) (56.7%)
B. malayi (n = 28)3 27/28 (96%) 7/18 (10 NC) (39%) 28/28 (100%) 27/27 (1NC) (100%)
O. volvulus (n = 20)4 11/16 (4 NC) (69%) 9/15 (5 NC) (60%) 0/20 (0%) 1/20 (5%)
Loa (n = 10)5 7/9 (1 NC) (78%) 3/7 (3 NC) (43%) 0/10 (0%) 0/9 (1 NC) (0%)
Other (incl. Strongyloides, Echinococcus; n = 20)6 0/19 (1 NC) (0%) 0/19 (1 NC) (0%) 0/20 (0%) 0/20 (0%)
  1. 1Specimens were collected from persons with documented infections with the listed parasites; for patients with filarial infections, microfilariae were detected. Abbreviations: NC, no consensus; specimens with a no consensus result were not included in the denominators for calculations.
  2. 2Geographic source of specimens provided in Table 2.
  3. 3Geographic source of specimens provided in Table 2.
  4. 4Ten specimens were from Guatemala and 10 were from Ecuador.
  5. 5Specimens were collected from patients in Benin.
  6. 6Echinococcus specimens were collected in Kenya; Strongyloides specimens were from several settings where lymphatic filariasis was not endemic.