Figure 1From: Diethylcarbamazine activity against Brugia malayimicrofilariae is dependent on inducible nitric-oxide synthase and the cyclooxygenase pathwayDEC causes rapid sequestration of B. malayi microfilariae in BALB/c mice. BALB/c mice intravenously injected with B. malayi microfilariae were dosed orally with 100 mg/kg DEC and microfilaraemia monitored from 5 to 60 minutes post treatment, then at 24 hours and two weeks.Back to article page