Figure 3
From: Cytokine profiles of filarial granulomas in jirds infected with Brugia pahangi
Levels of pro-inflammatory cytokine IL-6 released by granulomas. Granulomas were cultured in vitro for 6, 24, and 48 h with or without B. pahangi worm antigen. Cytokine levels were then measured in the supernatants of granuloma cultures using a B9-cell culture assay for IL-6. Results are expressed as counts per minute of [3H]thymidine incorporated, indicating the effect of granuloma-culture supernatants containing IL-6 on B9 cell growth. Supernatants from jird lymph node cells stimulated with Con-A and culture medium served as positive and negative controls.