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Table 2 LYMFASIM predictions of the number of annual mass drug treatment rounds required to achieve elimination in an area like Pondicherry, with 99% probability. Results are shown for four different drugs or drug combinations and two coverage levels. Predictions are based on the anti-L3 variant of the model for Pondicherry, with a precontrol microfilaraemia prevalence of 8.5%. Elimination is defined as zero microfilaraemia prevalence 40 years after the start of treatment. Source: [31]

From: Advances and challenges in predicting the impact of lymphatic filariasis elimination programmes by mathematical modelling

 

Assumed treatment effects (proportion killed)

Predicted number of rounds for elimination, with coverage

Drug(s)

adult worms

microfilariae

65%

80%

Ivermectin + albendazole

35%

100%

10

6

Diethylcarbamazine

50%

70%

8

5

Diethylcarbamazine + albendazole

65%

70%

6

4

Doxycycline

80%

0%

6

4