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Filaria Journal

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  1. Content type: Research

    The filarial parasites of major importance in humans contain the symbiotic bacterium Wolbachia and recent studies have shown that targeting of these bacteria with antibiotics results in a reduction in worm viabil...

    Authors: Simon Townson, Senyo Tagboto, Helen F McGarry, Gillian L Egerton and Mark J Taylor

    Citation: Filaria Journal 2006 5:4

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  2. Content type: Research

    Entomological methods may provide important tools for monitoring the transmission of filariasis in French Polynesia. In order to standardize our PCR method and refine our protocol to assess filarial infection ...

    Authors: Catherine Plichart, Yves Sechan, Neil Davies and Anne-Marie Legrand

    Citation: Filaria Journal 2006 5:2

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    The Erratum to this article has been published in Filaria Journal 2007 6:5

  3. Content type: Research

    Infection with the filarial nematode Onchocerca volvulus can lead to severe dermatitis, visual impairment, and ultimately blindness. Since the currently used drug, ivermectin does not have macrofilaricidal or str...

    Authors: Alexander Yaw Debrah, Sabine Mand, Yeboah Marfo-Debrekyei, John Larbi, Ohene Adjei and Achim Hoerauf

    Citation: Filaria Journal 2006 5:1

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  4. Content type: Research

    In the absence of intermediate animal hosts, the process of embryogenesis leading to fecundity of adult female filarial worms is very critical for persistence of these obligate parasites in human communities. ...

    Authors: Bikash Ranjan Sahu, Alok Das Mohapatra, Arindam Majumder, Pradip K Das and Balachandran Ravindran

    Citation: Filaria Journal 2005 4:11

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  5. Content type: Review

    An understanding of the nature of the chromosomes of the filariae is expected to greatly assist the future interpretation of genome data. Filarial development is not eutelic, and there does not seem to be a fi...

    Authors: Rory Post

    Citation: Filaria Journal 2005 4:10

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  6. Content type: Research

    Cystatins are reversible, tightly binding inhibitors of cysteine proteases. Filarial cystatins have been ascribed immunomodulatory properties and have been implicated in protective immunity. To continue explor...

    Authors: Smitha Pillai, Bernd H Kalinna, Eva Liebau, Susanne Hartmann, Franz Theuring and Richard Lucius

    Citation: Filaria Journal 2005 4:9

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  7. Content type: Research

    Ivermectin (Mectizan™, Merck and CO. Inc.) is being widely used in the control of human onchocerciasis (Onchoverca volvulus) because of its potent effect on microfilariae. Human studies have suggested that, at th...

    Authors: Barend M deC Bronsvoort, Alfons Renz, Virginia Tchakouté, Vincent N Tanya, David Ekale and Alexander J Trees

    Citation: Filaria Journal 2005 4:8

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  8. Content type: Short paper

    There has long been interest in determining if mass ivermectin administration for onchocerciasis has 'unknowingly' interrupted lymphatic filariasis (LF) transmission where the endemicity of the two diseases' o...

    Authors: FO Richards Jr, A Eigege, D Pam, A Kal, A Lenhart, JOA Oneyka, MY Jinadu and ES Miri

    Citation: Filaria Journal 2005 4:6

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  9. Content type: Research

    Annual mass drug administration (MDA) using diethylcarbamizine (DEC, 6 mg/kg) combined with albendazole (alb, 400 mg) is recommended by the Global Programme to Eliminate Lymphatic Filariasis (GPELF). This stra...

    Authors: Tim Oqueka, Taniawati Supali, Is Suhariah Ismid, Purnomo, Paul Rückert, Mark Bradley and Peter Fischer

    Citation: Filaria Journal 2005 4:5

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  10. Content type: Research

    Diethylcarbamazine (DEC) has been used for many years in the treatment of human lymphatic filariasis. Its mode of action is not well understood, but it is known to interact with the arachidonic acid pathway. H...

    Authors: Helen F McGarry, Leigh D Plant and Mark J Taylor

    Citation: Filaria Journal 2005 4:4

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  11. Content type: Short paper

    Our aim in this study was to observe the movements of filarial infective larvae following inoculation into the mammalian host and to assess the effect of vaccination on larval migration, in situ. Here we present ...

    Authors: Simon A Babayan, Tarik Attout, Phat N Vuong, Laetitia Le Goff, Jean-Charles Gantier and Odile Bain

    Citation: Filaria Journal 2005 4:3

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  12. Content type: Research

    Individuals with high microfilarial loads of Loa loa are at increased risk of neurologic serious adverse (SAE) events following ivermectin treatment against onchocerciasis. RAPLOA (Rapid Assessment Procedure for ...

    Authors: Samuel Wanji, Nicholas Tendongfor, Mathias Esum, Siker SJ Yundze, Mark J Taylor and Peter Enyong

    Citation: Filaria Journal 2005 4:2

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  13. Content type: Research

    Ultrasonography (USG) is known to be a suitable tool for diagnosis in lymphatic filariasis as the adult filarial nematode Wuchereria bancrofti in scrotal lymphatic vessels of infected men can be detected by the c...

    Authors: Sabine Mand, Yeboah Marfo-Debrekyei, Alex Debrah, Marcelle Buettner, Linda Batsa, Kenneth Pfarr, Ohene Adjei and Achim Hoerauf

    Citation: Filaria Journal 2005 4:1

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  14. Content type: Research

    The recombinant antigen BmR1 has been extensively employed in both ELISA and immunochromatographic rapid dipstick (Brugia Rapid) formats for the specific and sensitive detection of IgG4 antibodies against the lym...

    Authors: Rahmah Noordin, Ros Azeana Abdul Aziz and Balachandran Ravindran

    Citation: Filaria Journal 2004 3:10

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  15. Content type: Research

    The development of antifilarial antibody responses is a characteristic feature of infection with filarial parasites. It should be possible to exploit this fact to develop tools to monitor the progress of the g...

    Authors: Patrick J Lammie, Gary Weil, Rahmah Noordin, Perumal Kaliraj, Cathy Steel, David Goodman, Vijaya B Lakshmikanthan and Eric Ottesen

    Citation: Filaria Journal 2004 3:9

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  16. Content type: Research

    Brugia malayi is endemic in several Asian countries with the highest prevalence in Indonesia. Determination of prevalence of lymphatic filariasis by serology has been performed by various investigators using diff...

    Authors: Rahmah Noordin, Sitti Wahyuni, Andarias Mangali, Lim Boon Huat, Maria Yazdanbakhsh and Erliyani Sartono

    Citation: Filaria Journal 2004 3:8

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  17. Content type: Research

    Loa loa has recently emerged as a filarial worm of significant public health importance as a consequence of its impact on the African Programme for Onchocerciasis Control (APOC). Severe, sometimes fatal, encephal...

    Authors: Madeleine C Thomson, Valérie Obsomer, Joseph Kamgno, Jacques Gardon, Samuel Wanji, Innocent Takougang, Peter Enyong, Jan H Remme, David H Molyneux and Michel Boussinesq

    Citation: Filaria Journal 2004 3:7

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  18. Content type: Research

    Little information is available on methods of treatment practiced by patients affected by filarial lymphoedema in Sri Lanka. The frequency and duration of acute dematolymphangioadenitis (ADLA) attacks in these...

    Authors: TGA Nilmini Chandrasena, Ranjan Premaratna and Nilanthi R de Silva

    Citation: Filaria Journal 2004 3:6

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  19. Content type: Research

    In the global program for the elimination of lymphatic filariasis (LF) longitudinal assessment of the prevalence of microfilaremia and antigenemia is recommended to monitor the effect of mass treatment on tran...

    Authors: Charles H Washington, Jeanne Radday, Thomas G Streit, Heather A Boyd, Michael J Beach, David G Addiss, Rodrigue Lovince, Maribeth C Lovegrove, Jack G Lafontant, Patrick J Lammie and Allen W Hightower

    Citation: Filaria Journal 2004 3:3

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  20. Content type: Research

    Lymphatic filariasis (LF) affects more than 120 million people worldwide. Efforts to eliminate this disease require sustained community participation. This study explores community valuation of LF elimination ...

    Authors: Richard D Rheingans, Anne C Haddix, Mark L Messonnier, Martin Meltzer, Gladys Mayard and David G Addiss

    Citation: Filaria Journal 2004 3:2

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