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  1. Content type: Research

    Since 1991, in Mexico, ivermectin has been administered twice a year to all residents in the onchocerciasis endemic foci which are mainly located in the coffee growing areas. However, the presence of a potenti...

    Authors: Mario A Rodríguez-Pérez, Aldo Segura Cabrera, Cristian Lizarazo Ortega, María-Gloria Basáñez and John B Davies

    Citation: Filaria Journal 2007 6:16

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  2. Content type: Research

    Members of the Anopheles gambiae complex are important vectors of lymphatic filariasis (LF) in sub-Saharan Africa, but little is known about the relative contributions of all mosquitoes to lymphatic filariasis tr...

    Authors: Audrey Lenhart, Abel Eigege, Alphonsus Kal, D Pam, Emmanuel S Miri, George Gerlong, J Oneyka, Y Sambo, J Danboyi, B Ibrahim, Erica Dahl, D Kumbak, A Dakul, MY Jinadu, John Umaru, Frank O Richards…

    Citation: Filaria Journal 2007 6:14

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  3. Content type: Research

    Monitoring and evaluation are essential to the successful implementation of mass drug administration programmes for LF elimination. Monitoring transmission when it is low requires both large numbers of mosquit...

    Authors: Daniel A Boakye, Helena A Baidoo, Evans Glah, Charles Brown, Maxwell Appawu and Michael D Wilson

    Citation: Filaria Journal 2007 6:13

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  4. Content type: Research

    Mapping distribution of lymphatic filariasis (LF) is a prerequisite for planning national elimination programmes. Results from a nation wide mapping survey for lymphatic filariasis (LF) in Malawi are presented...

    Authors: Bagrey MM Ngwira, Phillimon Tambala, A Maria Perez, Cameron Bowie and David H Molyneux

    Citation: Filaria Journal 2007 6:12

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  5. Content type: Research

    In Sri Lanka filariasis is endemic in Southern, Western and North Western provinces covering eight districts designated as implementation units in the Programme for the Elimination of Lymphatic Filariasis (PEL...

    Authors: Mirani V Weerasooriya, Channa T Yahathugoda, Darshana Wickramasinghe, Kithsiri N Gunawardena, Rohan A Dharmadasa, Kanchana K Vidanapathirana, Saman H Weerasekara and Wilfred A Samarawickrema

    Citation: Filaria Journal 2007 6:11

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  6. Content type: Short paper

    In the global effort to eliminate lymphatic filariasis (LF), rapid field-applicable tests are useful tools that will allow on-site testing to be performed in remote places and the results to be obtained rapidl...

    Authors: Rahmah Noordin, Makoto Itoh, Eisaku Kimura, Rohana Abdul Rahman, Balachandran Ravindran, Rohela Mahmud, Taniawati Supali and Mirani Weerasooriya

    Citation: Filaria Journal 2007 6:9

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  7. Content type: Perspectives

    Lymphatic filariasis has been identified as one of the six diseases that can be potentially eliminated. Global programme to eliminate lymphatic filariasis has been launched, applying principal strategies of ma...

    Authors: A Krishna Kumari, K Krishnamoorthy, KT Harichandrakumar and LK Das

    Citation: Filaria Journal 2007 6:8

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  8. Content type: Research

    The recommended strategy for elimination of Lymphatic filariasis is single-dose, once-yearly mass treatment with anti-filarial drugs and the program is in operation on a national level in India. Rate of covera...

    Authors: B Nandha, C Sadanandane, P Jambulingam and PK Das

    Citation: Filaria Journal 2007 6:7

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  9. Content type: Research

    Lymphatic filariasis (LF) is a mosquito-borne disease caused by mosquito-transmitted filarial nematodes, including Wuchereria bancrofti and Brugia malayi. The Lymphatic Filariasis Elimination Program in Thailand ...

    Authors: Surang Nuchprayoon, Alisa Junpee and Yong Poovorawan

    Citation: Filaria Journal 2007 6:6

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  10. Content type: Perspectives

    Sustainable and equitable health programmes require a grounded understanding of the context in which they are being implemented. This socio-cultural understanding is pivotal for effective delivery of eliminati...

    Authors: Shona Wynd, David N Durrheim, Jaime Carron, Billy Selve, JP Chaine, Peter A Leggat and Wayne Melrose

    Citation: Filaria Journal 2007 6:3

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  11. Content type: Research

    Papua New Guinea is the only endemic country in the Western Pacific Region that has not yet introduced a countrywide programme to eliminate lymphatic filariasis. However, on Misima Island in Milne Bay Province...

    Authors: Shona Wynd, Jaime Carron, Billy Selve, Peter A Leggat, Wayne Melrose and David N Durrheim

    Citation: Filaria Journal 2007 6:1

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  12. Content type: Research

    In the Dominican Republic, a Latin American country with filariasis-endemic areas, more than 63,000 people have lymphatic filariasis and more than 400,000 people are at risk of future infection. In this paper,...

    Authors: Bobbie Person, David G Addiss, L Kay Bartholomew, Cecilia Meijer, Victor Pou and Bart van den Borne

    Citation: Filaria Journal 2006 5:13

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  13. Content type: Research

    The Global Programme to Eliminate Lymphatic Filariasis (GPELF) depends upon Mass Drug Administration (MDA) to interrupt transmission. Therefore, delimitation of transmission risk areas is an important step, an...

    Authors: Shanmugavelu Sabesan, Hari Kishan K Raju, AdiNarayanan Srividya and Pradeep Kumar Das

    Citation: Filaria Journal 2006 5:12

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  14. Content type: Review

    Through the Mectizan® Donation Program, Merck & Co., Inc. has donated Mectizan (ivermectin, MSD) for the treatment of onchocerciasis worldwide since 1987. Mectizan has also been donated for the elimination of lym...

    Authors: Mary M Alleman, Nana AY Twum-Danso and Björn I Thylefors

    Citation: Filaria Journal 2006 5:11

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  15. Content type: Perspectives

    There is a danger that mass drug administration campaigns may fail to maintain adequate treatment coverage to achieve lymphatic filariasis elimination. Hence, additional measures to suppress transmission might...

    Authors: TR Burkot, DN Durrheim, WD Melrose, R Speare and K Ichimori

    Citation: Filaria Journal 2006 5:10

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  16. Content type: Research

    Anopheles gambiae s.l. and An. funestus are important vectors of malaria and bancroftian filariasis, which occur as co-endemic infections along the Kenyan Coast. However, little is known about the occurrence and ...

    Authors: Ephantus J Muturi, Charles M Mbogo, Joseph M Mwangangi, Zipporah W Ng'ang'a, Ephantus W Kabiru, Charles Mwandawiro and John C Beier

    Citation: Filaria Journal 2006 5:8

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  17. Content type: Research

    Like other helminth proteases, filarial proteases have also been shown to require for parasite survival inside the host and mediate various physiologic processes such as tissue invasion, feeding, embryogenesis...

    Authors: Daya R Pokharel, Reeta Rai, Pankaj Kumar, C M Chaturvedi and Sushma Rathaur

    Citation: Filaria Journal 2006 5:7

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  18. Content type: Short paper

    It is well known that renal and neurological complications may occur after antifilarial treatment of patients infected with Loa loa. Conversely, spontaneous cases of visceral complications of loiasis have been ra...

    Authors: Tuna Lukiana, Madone Mandina, Nanituma H Situakibanza, Marcel M Mbula, Bompeka F Lepira, Wobin T Odio, Joseph Kamgno and Michel Boussinesq

    Citation: Filaria Journal 2006 5:6

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  19. Content type: Review

    Mathematical simulation models for transmission and control of lymphatic filariasis are useful tools for studying the prospects of lymphatic filariasis elimination. Two simulation models are currently being us...

    Authors: Wilma A Stolk, Sake J de Vlas and J Dik F Habbema

    Citation: Filaria Journal 2006 5:5

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  20. Content type: Research

    The filarial parasites of major importance in humans contain the symbiotic bacterium Wolbachia and recent studies have shown that targeting of these bacteria with antibiotics results in a reduction in worm viabil...

    Authors: Simon Townson, Senyo Tagboto, Helen F McGarry, Gillian L Egerton and Mark J Taylor

    Citation: Filaria Journal 2006 5:4

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  21. Content type: Research

    Entomological methods may provide important tools for monitoring the transmission of filariasis in French Polynesia. In order to standardize our PCR method and refine our protocol to assess filarial infection ...

    Authors: Catherine Plichart, Yves Sechan, Neil Davies and Anne-Marie Legrand

    Citation: Filaria Journal 2006 5:2

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    The Erratum to this article has been published in Filaria Journal 2007 6:5

  22. Content type: Research

    Infection with the filarial nematode Onchocerca volvulus can lead to severe dermatitis, visual impairment, and ultimately blindness. Since the currently used drug, ivermectin does not have macrofilaricidal or str...

    Authors: Alexander Yaw Debrah, Sabine Mand, Yeboah Marfo-Debrekyei, John Larbi, Ohene Adjei and Achim Hoerauf

    Citation: Filaria Journal 2006 5:1

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  23. Content type: Research

    In the absence of intermediate animal hosts, the process of embryogenesis leading to fecundity of adult female filarial worms is very critical for persistence of these obligate parasites in human communities. ...

    Authors: Bikash Ranjan Sahu, Alok Das Mohapatra, Arindam Majumder, Pradip K Das and Balachandran Ravindran

    Citation: Filaria Journal 2005 4:11

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  24. Content type: Review

    An understanding of the nature of the chromosomes of the filariae is expected to greatly assist the future interpretation of genome data. Filarial development is not eutelic, and there does not seem to be a fi...

    Authors: Rory Post

    Citation: Filaria Journal 2005 4:10

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  25. Content type: Research

    Cystatins are reversible, tightly binding inhibitors of cysteine proteases. Filarial cystatins have been ascribed immunomodulatory properties and have been implicated in protective immunity. To continue explor...

    Authors: Smitha Pillai, Bernd H Kalinna, Eva Liebau, Susanne Hartmann, Franz Theuring and Richard Lucius

    Citation: Filaria Journal 2005 4:9

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  26. Content type: Research

    Ivermectin (Mectizan™, Merck and CO. Inc.) is being widely used in the control of human onchocerciasis (Onchoverca volvulus) because of its potent effect on microfilariae. Human studies have suggested that, at th...

    Authors: Barend M deC Bronsvoort, Alfons Renz, Virginia Tchakouté, Vincent N Tanya, David Ekale and Alexander J Trees

    Citation: Filaria Journal 2005 4:8

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  27. Content type: Short paper

    There has long been interest in determining if mass ivermectin administration for onchocerciasis has 'unknowingly' interrupted lymphatic filariasis (LF) transmission where the endemicity of the two diseases' o...

    Authors: FO Richards Jr, A Eigege, D Pam, A Kal, A Lenhart, JOA Oneyka, MY Jinadu and ES Miri

    Citation: Filaria Journal 2005 4:6

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  28. Content type: Research

    Annual mass drug administration (MDA) using diethylcarbamizine (DEC, 6 mg/kg) combined with albendazole (alb, 400 mg) is recommended by the Global Programme to Eliminate Lymphatic Filariasis (GPELF). This stra...

    Authors: Tim Oqueka, Taniawati Supali, Is Suhariah Ismid, Purnomo, Paul Rückert, Mark Bradley and Peter Fischer

    Citation: Filaria Journal 2005 4:5

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  29. Content type: Research

    Diethylcarbamazine (DEC) has been used for many years in the treatment of human lymphatic filariasis. Its mode of action is not well understood, but it is known to interact with the arachidonic acid pathway. H...

    Authors: Helen F McGarry, Leigh D Plant and Mark J Taylor

    Citation: Filaria Journal 2005 4:4

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  30. Content type: Short paper

    Our aim in this study was to observe the movements of filarial infective larvae following inoculation into the mammalian host and to assess the effect of vaccination on larval migration, in situ. Here we present ...

    Authors: Simon A Babayan, Tarik Attout, Phat N Vuong, Laetitia Le Goff, Jean-Charles Gantier and Odile Bain

    Citation: Filaria Journal 2005 4:3

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  31. Content type: Research

    Individuals with high microfilarial loads of Loa loa are at increased risk of neurologic serious adverse (SAE) events following ivermectin treatment against onchocerciasis. RAPLOA (Rapid Assessment Procedure for ...

    Authors: Samuel Wanji, Nicholas Tendongfor, Mathias Esum, Siker SJ Yundze, Mark J Taylor and Peter Enyong

    Citation: Filaria Journal 2005 4:2

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  32. Content type: Research

    Ultrasonography (USG) is known to be a suitable tool for diagnosis in lymphatic filariasis as the adult filarial nematode Wuchereria bancrofti in scrotal lymphatic vessels of infected men can be detected by the c...

    Authors: Sabine Mand, Yeboah Marfo-Debrekyei, Alex Debrah, Marcelle Buettner, Linda Batsa, Kenneth Pfarr, Ohene Adjei and Achim Hoerauf

    Citation: Filaria Journal 2005 4:1

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  33. Content type: Research

    The recombinant antigen BmR1 has been extensively employed in both ELISA and immunochromatographic rapid dipstick (Brugia Rapid) formats for the specific and sensitive detection of IgG4 antibodies against the lym...

    Authors: Rahmah Noordin, Ros Azeana Abdul Aziz and Balachandran Ravindran

    Citation: Filaria Journal 2004 3:10

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  34. Content type: Research

    The development of antifilarial antibody responses is a characteristic feature of infection with filarial parasites. It should be possible to exploit this fact to develop tools to monitor the progress of the g...

    Authors: Patrick J Lammie, Gary Weil, Rahmah Noordin, Perumal Kaliraj, Cathy Steel, David Goodman, Vijaya B Lakshmikanthan and Eric Ottesen

    Citation: Filaria Journal 2004 3:9

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  35. Content type: Research

    Brugia malayi is endemic in several Asian countries with the highest prevalence in Indonesia. Determination of prevalence of lymphatic filariasis by serology has been performed by various investigators using diff...

    Authors: Rahmah Noordin, Sitti Wahyuni, Andarias Mangali, Lim Boon Huat, Maria Yazdanbakhsh and Erliyani Sartono

    Citation: Filaria Journal 2004 3:8

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  36. Content type: Research

    Loa loa has recently emerged as a filarial worm of significant public health importance as a consequence of its impact on the African Programme for Onchocerciasis Control (APOC). Severe, sometimes fatal, encephal...

    Authors: Madeleine C Thomson, Valérie Obsomer, Joseph Kamgno, Jacques Gardon, Samuel Wanji, Innocent Takougang, Peter Enyong, Jan H Remme, David H Molyneux and Michel Boussinesq

    Citation: Filaria Journal 2004 3:7

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  37. Content type: Research

    Little information is available on methods of treatment practiced by patients affected by filarial lymphoedema in Sri Lanka. The frequency and duration of acute dematolymphangioadenitis (ADLA) attacks in these...

    Authors: TGA Nilmini Chandrasena, Ranjan Premaratna and Nilanthi R de Silva

    Citation: Filaria Journal 2004 3:6

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  38. Content type: Research

    In the global program for the elimination of lymphatic filariasis (LF) longitudinal assessment of the prevalence of microfilaremia and antigenemia is recommended to monitor the effect of mass treatment on tran...

    Authors: Charles H Washington, Jeanne Radday, Thomas G Streit, Heather A Boyd, Michael J Beach, David G Addiss, Rodrigue Lovince, Maribeth C Lovegrove, Jack G Lafontant, Patrick J Lammie and Allen W Hightower

    Citation: Filaria Journal 2004 3:3

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  39. Content type: Research

    Lymphatic filariasis (LF) affects more than 120 million people worldwide. Efforts to eliminate this disease require sustained community participation. This study explores community valuation of LF elimination ...

    Authors: Richard D Rheingans, Anne C Haddix, Mark L Messonnier, Martin Meltzer, Gladys Mayard and David G Addiss

    Citation: Filaria Journal 2004 3:2

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